Purpose:
The purpose of this page is to provide a repository for quarantined text.
Experience:
- 7-years experience coaching myself (a consistent diet, exercise, financial life, etc.)
- 2-years experience coaching my partner
I am now coaching my first few clients (mostly family members, friends, and neighbors). Prices will increase as I’m able to share their testimonials, so if you are interested, I welcome you to contact me earlier rather than later.
Possible directions for this website include:
- Focusing on where to find the nutrients listed on this page in foods (mostly spices), teas, or elsewhere. Most food sources aren’t good enough and I’ll still recommend supplements.
- Focusing on modern health findings about women. Most of the biological sciences are based on males. Little is known about health as it relates to females, but this century, the floodgates will slowly open.
For now, of course, I recommend most Americans start with this page.
[Note: Remember that if the website author (a person, company, organization, whatever) wishes to use distraction as a tactic towards his/her/its overall strategy, that distraction/misdirection often begins on the “about” page. I want to draw attention to that. Be skeptical.]
Security
As I served in the USAF, I have great faith in the U.S. intelligence community. Unfortunately, the IC is led by the President, and therein lies a problem. I have very little trust in the current administration.
This is especially true considering we Americans elected the President under strong Russian influence (Search “ICA 2017_01” or click the link). If you’re an American, I strongly challenge you to print and read that document. It’s not a terribly long (a moderately spaced 20-something pages) or difficult read, and it gives a good window into both the IC and Russia’s goals for shaping the world. Most importantly, remember that you can only disagree with something like that if you’ve actually read it.
As such, if you know my phone number, I prefer to use Signal or WhatsApp to communicate. Open, unsecure calls are OK when urgent or convenient. Messaging with SMS/MMS or unsecure messaging programs are strongly discouraged.
And email is least secure of all, although I do have an @protonmail.com address.
(If you’re *adamant* about security, make sure to verify/exchange your contacts’ security codes/keys in person in the respective application, *physically* when you see them next. Otherwise, man-in-the-middle attacks are still possible, since you haven’t verified the end-user cryptographic key by putting the two phones/devices in physical contact.)
Lithium and Parkinson’s: Example References
Here are the references from the Parkinson’s chapter (8) of the book Greenblatt, James; Grossmann, Kayla. Nutritional Lithium: A Cinderella Story: The Untold Tale of a Mineral That Transforms Lives and Heals the Brain :
Andersen, J.K & Kim, H. (2013). U.S. Patent No. 0017274. Novato, CA: U.S. Patent and Trademark Office.
Bosco, D. A., Fowler, D. M., Zhang, Q., Nieva, J., Powers, E. T., Wentworth, P. J., & … Kelly, J. W. (2006). Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nature Chemical Biology, 2( 5), 249-253.
Buck Institute. (2015). Low dose lithium reduces side effects from most common treatment for Parkinson’s disease. Retrieved from www.buckinstitute.org/ buck-news/ low-dose-lithium-reduces-side-effects-most-common-treatment-parkinsons-disease
Coffey, C. E., Ross, D. R., Ferren, E. L., Sullivan, J. L., & Olanow, C. W. (1982). Treatment of the “on-off” phenomenon in Parkinsonism with lithium carbonate. Annals of Neurology, 12( 4), 375-379.
Dalén, P., & Steg, G. (1973). Lithium and levodopa in parkinsonism. Lancet, 1( 7809), 936-937. de Vasconcellos, A. S., Nieto, F. B., Crema, L. M., Diehl, L. A., de Almeida, L. M., Prediger, M. E., & … Dalmaz, C. (2006). Chronic lithium treatment has antioxidant properties but does not prevent oxidative damage induced by chronic variate stress. Neurochemical Research, 31( 9), 1141-1151.
Dwivedi, T., & Zhang, H. (2015). Lithium-induced neuroprotection is associated with epigenetic modification of specific BDNF gene promoter and altered expression of apoptotic-regulatory proteins. Frontiers in Neuroscience, 8, 457.
Fukumoto, T., Morinobu, S., Okamoto, Y., Kagaya, A., & Yamawaki, S. (2001). Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology, 158( 1), 100-106.
Jope, R. S., & Roh, M. (2006). Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Current Drug Targets, 7( 11), 1421-1434.
Kim, Y., Rane, A., Lussier, S., & Andersen, J. K. (2011). Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson’s disease. Journal of Neuroscience Research, 89( 10), 1666-1675.
Klein, C. & Westenberfer, A. (2012). Genetics of Parkinson’s disease. Cold Spring Harbor Perspectives in Medicine, 2( 1), a008888.
Kowal, S. L., Dall, T. M., Chakrabarti, R., Storm, M. V., & Jain, A. (2013). The current and projected economic burden of Parkinson’s disease in the United States. Movement Disorders, 28( 3), 311-318.
Lauterbach, E. C., Fontenelle, L. F., & Teixeira, A. L. (2012). The neuroprotective disease-modifying potential of psychotropics in Parkinson’s disease. Parkinson’s Disease, 2012, 753548.
Lazzara, C. A., & Yong-Hwan, K. (2015). Potential application of lithium in Parkinson’s and other neurodegenerative diseases. Frontiers in Neuroscience, 9, 403.
Lazzara, C. A., Riley, R. R., Rane, A., Andersen, J. K., & Kim, Y. (2015). The combination of lithium and l-Dopa/ Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson’s disease therapy. Brain Research, 1622, 127-136.
Leyhe, T., Eschweiler, G. W., Stransky, E., Gasser, T., Annas, P., Basun, H., & Laske, C. (2009). Increase of BDNF serum concentration in lithium treated patients with early Alzheimer’s disease. Journal of Alzheimer’s Disease, 16( 3), 649-656.
McCaul, J. A., & Stern, G. M. (1974). Letter: Lithium in Parkinson’s disease. Lancet, 1( 7866), 1117.
Mischley, L. (2012). Lithium deficiency in Parkinson’s disease. University of Washington MPH thesis. Unpublished.
Mischley, L. (2014). The Role of Lithium in Neurological Health and Disease. Journal of Orthomolecular Medicine, 29( 3), 101.
Murphy, L. et al. (2015). Deaths: Final data for 2012. Centers for Disease Control National Vital Statistics Reports, 63( 9), 1-118.
Nakabeppu, Y., Tsuchimoto, D., Yamaguchi, H., & Sakumi, K. (2007). Oxidative damage in nucleic acids and Parkinson’s disease. Journal of Neuroscience Research, 85( 5), 919-934.
National Institutes of Health (NIH). (2015). Levodopa and Carbidopa. MedlinePlus. Retrieved from www.nlm.nih.gov/ medlineplus/ druginfo/ meds/ a601068. html
Quinn, N. & Marsden, C. D. (1986). Lithium for painful dystonia in Parkinson’s disease. Lancet, 1( 8494), 1377.
Ravikumar, B., Sarkar, S., Davies, J. E., Futter, M., Garcia-Arencibia, M., Green-Thompson, Z. W., & … Rubinsztein, D. C. (2010). Regulation of mammalian autophagy in physiology and pathophysiology. Physiological Reviews, 90( 4), 1383-435.
Scalzo, P., Kummer, A., Bretas, T. L., Cardoso, F., & Teixeira, A. L. (2010). Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson’s disease. Journal of Neurology, 257( 4), 540.
Sarkar, S., Floto, R. A., Berger, Z., Imarisio, S., Cordenier, A., Pasco, M., & … Rubinsztein, D. C. (2005). Lithium Induces Autophagy by Inhibiting Inositol Monophosphatase. Journal of Cell Biology, 170( 7), 1101-11.
Tanner, C. M. (2011). Environmental factors and Parkinson’s: What have we learned? Parkinson’s Disease Foundation Newsletter. Spring 2011.
Thanvi, B., Lo, N., & Robinson, T. (2007). Levodopa-induced dyskinesia in Parkinson’s disease: clinical features, pathogenesis, prevention and treatment. Postgraduate Medical Journal, 83( 980), 384-388.
Van Woert, M. H., & Ambani, L. M. (1973). Lithium and levodopa in parkinsonism. Lancet, 1( 7816), 1390-1391.
lithium in biology
Specific Purposes:
The purpose of this is to share information about lithium in biology to both
- The general American public, to a) promote an awareness of lithium as an essential mineral, and b) to recommend supplementation at or below the RDA level (see my recommendations here), and
- Scientists, to a) provoke/promote an acceptance of the nutritional need for the mineral, and b) to help arouse creative scientific thought and inquiry regarding lithium’s role in biological processes.
Table of Contents
section1
section2
support page /support
Purpose: the purpose of this page is to explain my philosophy regarding income.
If you’ve stumbled onto this page, you can ignore it. I removed the old links because I want people to focus on the quality behind the /pills page, and if I earn money from that, great. If not, I’ll focus on learning to program.
(See the now page for what I’m currently working on.)
Starting a personal website in 2017 means entering a very crowded space. Unfortunately, I loathe the current status of advertising on the web. I hope a fair, respectable content payment model becomes popular someday, but I’m not holding my breath. [March 2017: Stumbled on Patreon, which I like and may use in the future if/when I’m generating enough quality “content.”]
Moreover, I have been happily “unemployed” since 2013. However, the savings I accrued in my early 20s (bio page), while substantial, are beginning to wane. If I generate no income based on donations, programming, or business ideas, I may have to sell my time to the highest bidder. That’s the system we’ve been using for thousands of years, and I don’t like it.
The biggest costs to running this website and projects are personal:
- Rent. I don’t have to live in the tri-state area, but I’m committed and ecstatic to do it for 1-3 years. I love NYC!
- Food. I eat high quality (but not extravagant) food, don’t compromise, and supplement.
- Most Americans spend a mere 7% of their income on food (the lowest in the world), and then complain and remain confused as to why they don’t enjoy how their bodies physically feel. For most of my adult life I have spent between 20-30% of my monthly income (or budget) on food. I eat mostly self-cooked food at home.
As such, I’m currently open to donations.
(Again, see the now page for what I’m currently working on.)
- How much? Donate what you’d like:
- A refreshing beverage (<$9),
- A lunch or snack (<$19),
- An expensive dinner at Per Se ($800) or another “prix fixe,”
- A respectable annual salary ($100-200,000).
- Donate a recurring amount:
- $5/month
- $10/month
- $100/month
- $1,000-10,000/month
- Donate a gift, or donate the amount to cover the gift.
- I haven’t read Stratfor.com for a while, and I love staying current with geopolitics. It’s about $350/yr, although this isn’t as important to me in 2017 as it will be in the future.
- I have an 80-lb kettlebell, but I’d love a 90- or 100-lb. Heavy, but expensive and unnecessary for me right now. I’d use it if it were a gift, however!
- Other random gifts. Remember that experiences are always better than physical gifts:
- We’d gladly see the musicals Phantom of the Opera or Wicked any day of the week in any seat. We’d also love to see Fiddler on the Roof again.
- Tall buildings in NYC. That never gets old. We’ve been to the top of 1WTC (The thick glass disconnects you from the view. “Meh.”), but not yet to the “Top of the Rock.”
- NYC’s museums. Ask me where I have and haven’t been; the good ones are mostly PWYW so you need not worry about those.
- I don’t like extravagant food, but I love the occasional prix fixe tasting menu. I love good food, and when eating out, I absolutely detest making decisions about the food. I believe menus with more than a few options in more than a few categories are doing more of a disservice to their patrons than anything, and I’d bet money they’ll go away in the next few decades!
A bitcoin address will soon follow:
xxxxxxxxxxxxxx
Thanks!
John
(Again, see the now page for what I’m currently working on.)
Curious why the links have my amazon.com Affiliate Program tracking code in them?
Outgoing Donations:
Tim Ferriss’ 2015 interview with Will MacAskill convinced me to spend the time to learn about GiveWell.org and donate a small amount of my savings to their highest rated charities.
Did it give me warm fuzzy altruistic feelings all over? Absolutely. Still, donating 1-2% of my net worth, while unemployed and living/traveling off of my savings, was at least a slightly nerve wracking decision.
Another benefit: while in South America, it made it far easier to say “no” to street beggars. “No. I do not under any circumstances donate in the street” I would memorize and rehearse (in Spanish, too) in order to reject beggars, although my resolve faltered a few times and I did indeed donate food or money. That still happens on occasion. In any case, I gained a reflex/instinct I’m happy to have now that I’m back in the United States.
When you donate from the privacy of your own home, saying “no” in the street, day to day, doesn’t feel bad at all.
As such, my current goal is to donate at least a small percentage of my time or earnings: let’s say between 2-10% annually. If/when I have a salary exceeding $100,000/year, I hope to increase that percentage well above 10% of annual earnings.
Update Log:
7 March 2017, donation section and misc edits.
12 February, 2017 [created]
Comments & Feedback
Comments on individual pages are disabled. I apologize, but it’s too difficult to sort through them all. However, I encourage your feedback and will respond to it (or make suggested changes) as applicable. Please use the /contact page or contact me directly.
Update Log